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Common uses

Duphaston is used for several different menstrual disorders that occur due to a lack of progesterone in the body. Dydrogesterone is necessary for the maintenance of a healthy endometrium, the lining of the uterus, required for pregnancy. The body produces Dydrogesterone at certain times of the month, making the uterus hospitable to a fertilized embryo. If no embryo appears, progesterone levels drop and the body sheds the lining of the uterus, resulting in a menstrual period. Taking Duphaston helps to regulate this process in women whose progesterone levels are low, so that they may be maintained at the level required for health and fertility.

Duphaston is used as a treatment for several different conditions related to progesterone production. If a woman experiences abdominal pain or bleeding during a pregnancy, or if she is pregnant but has a history of miscarriages, Duphaston can help sustain the necessary levels of hormones required to maintain a healthy pregnancy. It also relieves severe menstrual cramps or regulates menstrual periods if you have difficulty in these matters due to a progesterone deficiency. It helps treat endometriosis, an inflammation of the lining of the uterus, and helps regulate irregular menstrual cycles. It can stabilize the level of progesterone, thereby treating premenstrual syndrome. It also can help prevent the excessive growth of the endometrium that is a result of estrogen hormone replacement therapy. It is also used to treat infertility in women by re-establishing the levels of progesterone required for women to become pregnant.

Before using

Irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency.
Combined with an estrogenic substance, Duphaston can be applied in secondary amenorrhoea, dysfunctional uterine bleeding and post-menopausal complaints where endogenous progesterone deficiency is implicated.

Directions

In general
The dosage schemes below are meant as general recommendations. For optimal therapeutic effect, the dosages are to be adapted to the nature and severity of the disorder.
In irregular cycles due to endogenous progesterone deficiency
Duphaston 5 to 10 mg is recommended especially in irregular cycles due to shortened luteal phase (ie pre-menopause). Treatment should be repeated for several cycles.
In secondary amenorrhoea
Administration of Duphaston in combination with an estrogen is usually recommended as in these conditions endogenous progesterone deficiency is nearly always accompanied by estrogen deficiency. 0,05 mg ethinylestradiol is administered each day from the 1st to the 25th day of the cycle, and 5 mg Duphaston is added twice daily from the 11th to the 25th day. Five days after the subsequent withdrawal bleeding, the same is repeated to imitate a natural cycle.
In dysfunctional uterine bleeding
The symptomatic treatment is aimed at stopping the bleeding and including a subsequent withdrawal bleeding.
To stop bleeding: Duphaston 10 mg together with 0,10 mg ethinylestradiol twice daily for 5 to 7 days.
To prevent heavy bleedings: Duphaston 5 mg twice daily from day 11 to day 25 of the cycle, if necessary, combined with an estrogen during the first half of the cycle.
In post-menopausal complaints
If for the symptomatic treatment of post-menopausal complaints estrogens are used (hormone replacement therapy � HRT), Duphaston 10 mg is used to counteract the effects of unopposed estrogens on the endometrium. A subsequent withdrawal bleeding is induced.
If on continuous estrogen therapy: Duphaston 10 mg twice daily during the first 12 to 14 days of each calendar month.
If on cyclic estrogen therapy: Duphaston 10 mg twice daily during the last 12 to 14 days of the treatment.

Cautions

Duphaston should not be given to patients with undiagnosed vaginal bleeding nor to those with a history of thromboembolic disorders.
Duphaston should be used with caution in patients with cardiovascular, renal or hepatic impairment, diabetes mellitus, asthma, epilepsy and migraine. It should be used with care in persons with a history of mental depression.
Store in a dry, dark place at temperatures not exceeding 25�C. Keep out of reach of children.

Possible side effects

Side effects of Duphaston may include gastro-intestinal disturbances, allergic skin rashes or urticaria, changes in libido, acne, fluid retention, mass gain, mental depression and breast changes, which may include discomfort or gynaecomastia. Alterations in liver function tests have been reported and less frequently jaundice.
In a small percentage of the treated cases, breakthrough bleeding may occur, which can be prevented by increasing the dosage. During the clinical application of Duphaston, no virilising side effects were observed.

If you take too much

See ' Possible side effects '. Treatment is symptomatic and supportive.

Additional information

Duphaston should be used with caution in patients with cardiovascular, renal or hepatic impairment, diabetes mellitus, asthma, epilepsy and migraine. It should be used with care in persons with a history of mental depression.

Drug interactions

There are no reported significant interactions with this medicine.

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Common uses

Verapamil is used to treat irregular heartbeats (arrhythmias) and high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart to control chest pain (angina). If taken regularly, verapamil controls chest pain, but it does not stop chest pain once it starts. Your doctor may give you a different medication to take when you have chest pain.

Before using

Before taking this medication, tell your doctor if you have
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You may not be able to take verapamil, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above

Directions

This medication should be swallowed whole with a full glass of water unless your doctor directs you otherwise. This medication must be taken as directed to prevent chest pain. It is not effective if taken only when chest pain occurs. Do not stop taking this medication suddenly without your doctor's permission. Chest pain can occur if the medication is stopped too fast. Your dose may need to be gradually decreased.

Cautions

Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), heart problems (e.g., heart rhythm disturbances, heart failure), liver or kidney disease, very low blood pressure, muscular dystrophy, brain tumors (cancer). Before heart surgery, tell your doctor you use this medicine. Verapamil prolongs and intensifies the effects of alcohol in your system. Avoid (or very carefully limit) alcoholic beverages while using this medication. Caution is advised when this drug is used in the elderly. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and a decision should be made whether to stop the drug or avoid breast-feeding. Consult your doctor before breast-feeding.

Possible side effects

This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness. You may also experience weakness, fatigue, nausea, muscle cramps, headache, flushing or constipation. These effects should disappear as your body adjusts to the medication. Inform your doctor if they become bothersome. Notify your doctor immediately if you develop: breathing difficulties, swelling of the hands or feet, irregular heartbeat, fever, stomach/abdominal pain, yellowing eyes and skin, dark urine. If you notice other effects not listed above, contact your doctor or pharmacist.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include rapid, slow, or irregular heartbeat; dizziness; fainting; and loss of consciousness.

Additional information

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to verapamil.
Your doctor may ask you to check your pulse (heart rate) daily and will tell you how fast it should be. If your pulse is slower than it should be, call your doctor for directions on taking verapamil that day. Ask your doctor or pharmacist to teach you how to check your pulse.
The extended-release tablet (Covera) does not dissolve in the stomach after being swallowed. It slowly releases medicine as it passes through the small intestines. It is not unusual to see the tablet shell eliminated in the stool.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug interactions

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: beta-blockers, intravenous (IV) calcium, cimetidine, cyclosporine, digoxin. Avoid any drugs that increase your heart-rate (the decongestants phenylephrine, pseudoephedrine and phenylpropanolamine are examples). These drugs are commonly found in over-the-counter cough-and-cold products. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.


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Common uses

Cymbalta is used for treating depression and generalized anxiety disorder. It is used for managing pain caused by diabetic peripheral neuropathy (DPNP). It may also be used for other conditions as determined by your doctor.

Before using

Do not use Cymbalta together with thioridazine (Mellaril), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with Cymbalta. You must wait at least 14 days after stopping an MAO inhibitor before you can take Cymbalta. After you stop taking Cymbalta, you must wait at least 5 days before you start taking an MAOI. Do not use this medication if you are allergic to duloxetine, or if you have untreated or uncontrolled glaucoma.
Before taking Cymbalta, tell your doctor if you are allergic to any drugs, or if you have:
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If you have any of these conditions, you may need a dose adjustment or special tests to safely take Cymbalta.
You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.
Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Directions

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from the medication.
Try to take the medicine at the same time each day. Follow the directions on your prescription label.
Do not crush, chew, break, or open a delayed-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time. It may take 4 weeks or longer for your symptoms to improve. For best results, keep using the medication as directed. Do not stop using Cymbalta without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly. Store Cymbalta at room temperature away from moisture and heat.

Cautions

Avoid drinking alcohol while taking Cymbalta. Alcohol may increase the risk of damage to your liver. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Cymbalta. Tell your doctor if you regularly use any of these other medicines. Cymbalta can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Possible side effects

Like most medications, there are some side effects associated with Cymbalta. Most side effects - if they do occur - will resolve after the body becomes adjusted to the medication, usually in a couple of weeks. In clinical trials, the most commonly reported side effects include:
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�fatigue
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�increased sweating
�sexual side-effects
�possible withdrawal symptoms if abruptly discontinued
While not common, there have been reported cases of elevated blood pressure when taking Cymbalta. Your doctor will monitor your blood pressure while taking the drug.


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Seek emergency medical attention if you think you have taken too much of this medication. Overdose symptoms may include nausea, vomiting, diarrhea, agitation, confusion, hallucinations, fast heart rate, feeling light-headed, or fainting.

Additional information

Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI). It works by restoring the balance of certain natural substances in the brain (serotonin and norepinephrine), which helps to improve certain mood problems.

Drug interactions

Do not take Cymbalta together with thioridazine (Mellaril), or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate). You must wait at least 14 days after stopping an MAOI before you can take Cymbalta. After you stop taking Cymbalta, you must wait at least 5 days before you start taking an MAOI.
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Domperidone is to be given only by or under the immediate supervision of your doctor. It is available in the following dosage forms:
�Oral
�Tablets (Canada)

Common uses

This medicine contains the active ingredient domperidone, which is a type of medicine called a dopamine antagonist. It is an anti-emetic medicine, meaning it is used to treat nausea and vomiting. It can also be used to treat abdominal bloating, fullness and discomfort in adults.

Domperidone works primarily by blocking dopamine receptors found in an area of the brain known as the chemoreceptor trigger zone (CTZ). The CTZ is activated by nerve messages from the stomach when an irritant is present. It is also activated directly by agents circulating in the blood, for example anti-cancer medicines. Once activated, it sends messages to another area of the brain, the vomiting centre, which in turn sends messages to the gut, causing the vomiting reflex.

Before using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For domperidone the following should be considered:
Allergies�Tell your doctor if you have ever had any unusual or allergic reaction to domperidone.
Pregnancy�domperidone has not been studied in pregnant women. However, domperidone has not been shown to cause birth defects or other problems in animal studies.
Breast-feeding�Domperidone passes into the breast milk, but it is not known if domperidone will cause unwanted effects in the newborn. It may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.
Children�Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of domperidone in children with use in other age groups.
Older adults�Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of domperidone in the elderly with use in other age groups.
Other medicines�Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your doctor or pharmacist if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially:
�Monoamine oxidase (MAO) inhibitors (furazolidone [e.g., Furoxone], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegilene [e.g., Eldepryl], tranylcypromine [e.g., Parnate])
Other medical problems�The presence of other medical problems may affect the use of domperidone. Make sure you tell your doctor if you have any other medical problems, especially:
�Bleeding from the stomach or other problems involving the bowels
�Pituitary (brain) tumor
�Liver disease
�Medicine sensitivity to domperidone

Directions

The usual adult dose of domperidone is 10 mg three to four times a day, taken 15 to 30 minutes before meals and at bedtime if required. The dose sometimes needs to be increased to 20 mg four times a day. When treating the nausea and vomiting associated with medications used to treat Parkinson's disease, the usual adult dosage is 20 mg three or four times a day.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.
It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses.

Cautions

This medicine is not recommended for long term use.
Motilium tablets contain lactose and may be unsuitable for people with lactose intolerance, glucose/galactose malabsorption or a genetic disorder leading to accumulation of galactose in the blood (galactosaemia). Motilium suspension contains sorbitol and may be unsuitable for people with sorbitol intolerance.
Possible side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
�Diarrhoea
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�Abnormal movements of the hands, legs, face, neck and tongue, eg tremor, twitching, rigidity (extrapyramidal effects)
�Breast pain
�High blood prolactin (milk producing hormone) level (hyperprolactinaemia). Sometimes this can lead to symptoms such as breast enlargement, production of milk and stopping of menstrual periods.
�Stomach cramps
�Decreased sex drive
�Itchy rash (urticaria)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.


If you take too much

Symptoms of overdosage may include drowsiness, disorientation and extrapyramidal reactions especially in children.
Anticholinergic, anti-Parkinson medicines or antihistamines with anticholinergic properties may be helpful in controlling the extrapyramidal reactions. There is no specific antidote to domperidone but in the event of overdosage, gastric lavage as well as the administration of activated charcoal may be useful. Symptomatic and supportive measures are recommended.

Additional information

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
�The safety of this medicine for use during pregnancy has not been established. It is not recommended for use in pregnancy unless considered essential by your doctor. Seek medical advice from your doctor.
�This medicine passes into breast milk in small amounts. Seek medical advice from your doctor before breastfeeding.

Drug interactions

The following medications may affect how domperidone works or increase the risk of side effects:
�azole' antifungals (e.g., fluconazole, itraconazole, ketoconazole, miconazole)
�erythromycin antibiotics (e.g., clarithromycin)
�HIV protease inhibitors (e.g., indinavir)
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If you are taking any of these medications, speak with your doctor or pharmacist.
Depending on your specific circumstances, your doctor may want you to:
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Common uses

Micardis is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.
Micardis may also be used for other purposes not listed here.

Before using

You should not use Micardis if you are allergic to telmisartan.
Before using Micardis, tell your doctor if you are allergic to any drugs, or if you have:
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If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
FDA pregnancy category D. This medication can cause harm to an unborn baby. Micardis may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Do not use Micardis without your doctor's consent if you are pregnant. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether Micardis passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Directions

Take this medication by mouth, usually once daily or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur. The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 4 weeks before the full benefit of this drug occurs. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Cautions

Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Micardis. Do not use potassium supplements or salt substitutes while you are taking Micardis, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
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Additional information

Do not use this medication without telling your doctor if you are pregnant. Micardis may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using Micardis and tell your doctor right away if you become pregnant during treatment. You should not use this medication if you are allergic to telmisartan. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Micardis. Do not use potassium supplements or salt substitutes while you are taking Micardis, unless your doctor has told you to.

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Before taking Micardis, tell your doctor if you are using any of the following drugs:
�a diuretic (water pill);
�digoxin (digitalis, Lanoxin); or
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The styptic and astringent properties of Styplon, combined with anti-inflammatory and demulcent actions, facilitate hemostasis and help in the effective management of bleeding. Styplon tablets are useful when the following symptoms are displayed: bleeding gums; bleeding hemorrhoids; epistaxis; abnormal uterine bleeding or spotting; hematuria; hemoptysis as an adjuvant.

Directions

Take Styplon 3 times a day 2-3 tablets for 2-4 days until the bleeding is under control. The dosage can then be reduced to 2 times a day 1-2 tablets for 2-4 weeks. Half the dose for children.

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No absolute contraindications. Consult your healthcare professional if pregnant or nursing.

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Fifty patients who visited the out-patient were followed up periodically once a month for a period of six months for evidence of recurrence of bleeding from the gums. No bleeding from the gums was noticed in these patients, except in two patients who complained of slight oozing during brushing. The maintenance of oral hygiene was comparatively poor in those patients.


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Seroquel may also be used for purposes other than those listed in this medication guide.

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Seroquel is not for use in psychotic conditions that are related to dementia. Seroquel has caused fatal pneumonia or heart failure in older adults with dementia-related conditions.
Before you take Seroquel, tell your doctor if you have:
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You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.
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You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

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Additional information

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�thioridazine (Mellaril);
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�medicine for depression or mental illness, such as fluoxetine (Prozac), haloperidol (Haldol), imipramine (Tofranil), or risperidone (Risperdal);
�a medication to treat high blood pressure or a heart condition; or
�seizure medication such as carbamazepine (Tegretol), divalproex (Depakote), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), or valproate (Depakene).
This list is not complete and there may be other drugs that can interact with Seroquel. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


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Tags: Can you buy Plendil with with a subscription, Buy online pharmacy Plendil. Cheapest Plendil prices licensed pharmacies, Discount sildenafil generic Plendil, Buy Plendil online cheap, Best price for Plendil, Buy Plendil low cost, Order Plendil online, Buy Plendil cheap fed ex, Discount drugs Plendil, Buy Plendil on line, Plendil online prescription, Where to buy generic Plendil, Comprar Plendil, Plendil compare price, On line Plendil, Generic Plendil soft, Buying Plendil without a perscription, Cheapest Plendil in uk, Cheap est Plendil, Buy Plendil professional, Get Plendil, Buy real Plendil online, Plendil purchase, Best place to buy Plendil online, Cheap Plendil online, Generic Plendil cheapest, Cheapest generic substitute Plendil, Online prescription Plendil, Online cheap Plendil buy, Buy Plendil pharmacy online, Generic Plendil soft, Buy Plendil softPlendil (FELODIPINE) contains the active ingredient felodipine, which is a type of medicine called a calcium channel blocker. This type of medicine acts on the heart and blood vessels.

Felodipine works by slowing the movement of calcium through the muscle cells that are found in the walls of blood vessels. It acts specifically on the muscle cells in the walls of small arteries (arterioles). Felodipine slows calcium movement by blocking 'calcium channels' in these muscle cells. Calcium is needed by muscle cells in order for them to contract, so felodipine causes the muscle in the walls of the small arteries to relax. This widens the small arteries in the body, an effect that has two uses.

The relaxing and widening of the small arteries in the body decreases the resistance that the heart has to push against in order to pump the blood around the body. This reduces blood pressure. Felodipine can therefore be used to treat high blood pressure.

The widening effect on the small arteries also improves the blood and therefore oxygen supply to the heart. This feature means felodipine can be used to treat angina. The chest pain of angina is caused by insufficient oxygen supply to the heart. As felodipine improves this oxygen supply, and also reduces the effort the heart has to make to pump blood, it can be used to prevent angina attacks.

Common uses

Plendil is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Felodipine is known as a calcium channel blocker. By blocking calcium, this medication relaxes and widens blood vessels so blood can flow more easily.

Before using

Before taking Plendil, tell your doctor if you have liver disease; or another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.

You may not be able to take Plendil, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Plendil is in the FDA pregnancy category C. This means that it is not known whether Plendil will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether Plendil passes into breast milk. Do not take Plendil without first talking to your doctor if you are breast-feeding a baby.

If you are over 65 years of age, you may be more likely to experience side effects from Plendil. Your doctor may prescribe a lower dose of this medication.

Directions

The recommended adult dose of felodipine ranges from 2.5 mg to 10 mg once daily, swallowed whole (not crushed or chewed) and taken with or without food. The tablets should not be taken with a meal that is high in carbohydrates or fat (e.g., sausages, bacon, hash browns, or sugared cereals). Grapefruit juice increases the amount of felodipine in your body and should be avoided.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Cautions

Do not stop taking this medicine without checking with your doctor. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. While you are using this medicine, brush and floss your teeth carefully. Also, have regular dental check-ups. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist.
For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if this drug is excreted in breast milk. Do not breast-feed while taking this medicine.

Possible side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
�Worsening of anginal chest pains
�Impotence
�Fatigue
�Awareness of your heart beat (heart palpitations)
�Dizziness
�Flushing
�Enlargement of the gums (gingival hyperplasia)
�Rash or itching
�Headache
�Ankle swelling
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dizziness, weakness, slowed or irregular heartbeat, nausea, drowsiness, confusion, and slurred speech.

Additional information

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.

Drug interactions

Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

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